1GIS

A TRICHOSANTHIN(TCS) MUTANT(E85Q) COMPLEX STRUCTURE WITH 2'-DEOXY-ADENOSIN-5'-MONOPHOSPHATE

Summary for 1GIS

Related1GIU
DescriptorRIBOSOME-INACTIVATING PROTEIN ALPHA-TRICHOSANTHIN, 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE (3 entities in total)
Functional Keywordsprotein-sub complex, trichosanthin, tcs, hydrolase
Biological sourceTrichosanthes kirilowii
Total number of polymer chains1
Total molecular weight27628.2
Authors
Guo, Q.,Liu, Y.,Dong, Y.,Rao, Z. (deposition date: 2001-03-15, release date: 2003-06-03, Last modification date: 2011-07-13)
Primary citation
Guo, Q.,Zhou, W.,Too, H.M.,Li, J.,Liu, Y.,Bartlam, M.,Dong, Y.,Wong, K.B.,Shaw, P.C.,Rao, Z.
Substrate binding and catalysis in trichosanthin occur in different sites as revealed by the complex structures of several E85 mutants.
Protein Eng., 16:391-396, 2003
PubMed: 12874371 (PDB entries with the same primary citation)
DOI: 10.1093/protein/gzg056
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.7 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers190.4%2.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution