1GC5

CRYSTAL STRUCTURE OF A NOVEL ADP-DEPENDENT GLUCOKINASE FROM THERMOCOCCUS LITORALIS

1GC5 の概要

• エントリーDOI: 10.2210/pdb1gc5/pdb
• 分子名称: ADP-DEPENDENT GLUCOKINASE, ADENOSINE-5'-DIPHOSPHATE (3 entities in total)
• 機能のキーワード: alfa/beta sandwichs, induced-fitting, transferase
• 由来する生物種: Thermococcus litoralis
• 細胞内の位置: Cytoplasm (By similarity): Q7M537
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 54045.29

構造登録者

Ito, S.,Fushinobu, S.,Yoshioka, I.,Koga, S.,Matsuzawa, H.,Wakagi, T. (登録日: 2000-07-20, 公開日: 2001-07-25, 最終更新日: 2023-12-27)

主引用文献

Ito, S.,Fushinobu, S.,Yoshioka, I.,Koga, S.,Matsuzawa, H.,Wakagi, T.
Structural Basis for the ADP-Specificity of a Novel Glucokinase from a Hyperthermophilic Archaeon
Structure, 9:205-214, 2001

PubMed Abstract: ATP is the most common phosphoryl group donor for kinases. However, certain hyperthermophilic archaea such as Thermococcus litoralis and Pyrococcus furiosus utilize unusual ADP-dependent glucokinases and phosphofructokinases in their glycolytic pathways. These ADP-dependent kinases are homologous to each other but show no sequence similarity to any of the hitherto known ATP-dependent enzymes.

PubMed: 11286887
DOI: 10.1016/S0969-2126(01)00577-9

実験手法

X-RAY DIFFRACTION (2.3 Å)