1G96
HUMAN CYSTATIN C; DIMERIC FORM WITH 3D DOMAIN SWAPPING
Summary for 1G96
Entry DOI | 10.2210/pdb1g96/pdb |
Related | 1a67 1cew 1dvc 1stf |
Descriptor | CYSTATIN C, CHLORIDE ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | human cystatin c dimer, 3d domain swapping, amyloid formation, inhibitor of c1 and c13 cysteine proteases, amyloid angiopathy and cerebral hemorrhage, hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P01034 |
Total number of polymer chains | 1 |
Total formula weight | 13492.69 |
Authors | Janowski, R.,Kozak, M.,Jankowska, E.,Grzonka, Z.,Grubb, A.,Abrahamson, M.,Jaskolski, M. (deposition date: 2000-11-22, release date: 2001-04-06, Last modification date: 2023-08-09) |
Primary citation | Janowski, R.,Kozak, M.,Jankowska, E.,Grzonka, Z.,Grubb, A.,Abrahamson, M.,Jaskolski, M. Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping. Nat.Struct.Biol., 8:316-320, 2001 Cited by PubMed: 11276250DOI: 10.1038/86188 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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