1G2O

CRYSTAL STRUCTURE OF PURINE NUCLEOSIDE PHOSPHORYLASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH A TRANSITION-STATE INHIBITOR

1G2O の概要

• エントリーDOI: 10.2210/pdb1g2o/pdb
• 分子名称: PURINE NUCLEOSIDE PHOSPHORYLASE, PHOSPHATE ION, 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, ... (4 entities in total)
• 機能のキーワード: trimer, transition-state complex, transferase
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 83882.04

構造登録者

Shi, W.,Basso, L.A.,Tyler, P.C.,Furneaux, R.H.,Blanchard, J.S.,Almo, S.C.,Schramm, V.L. (登録日: 2000-10-20, 公開日: 2001-08-01, 最終更新日: 2023-09-20)

• 主引用文献: Shi, W.,Basso, L.A.,Santos, D.S.,Tyler, P.C.,Furneaux, R.H.,Blanchard, J.S.,Almo, S.C.,Schramm, V.L.; Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces.; Biochemistry, 40:8204-8215, 2001; PubMed: 11444966; DOI: 10.1021/bi010585p

実験手法

X-RAY DIFFRACTION (1.75 Å)