1G1X

STRUCTURE OF RIBOSOMAL PROTEINS S15, S6, S18, AND 16S RIBOSOMAL RNA

「1EKC」から置き換えられました

1G1X の概要

• エントリーDOI: 10.2210/pdb1g1x/pdb
• 分子名称: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S6, 30S RIBOSOMAL PROTEIN S15, ... (5 entities in total)
• 機能のキーワード: ribosomal proteins s15, s6, s18, s30 ribosomal subunit, rna, ribosome
• 由来する生物種: Thermus thermophilus; 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 120293.24

構造登録者

Agalarov, S.C.,Prasad, G.S.,Funke, P.M.,Stout, C.D.,Williamson, J.R. (登録日: 2000-10-13, 公開日: 2000-10-30, 最終更新日: 2024-02-07)

主引用文献

Agalarov, S.C.,Sridhar Prasad, G.,Funke, P.M.,Stout, C.D.,Williamson, J.R.
Structure of the S15,S6,S18-rRNA complex: assembly of the 30S ribosome central domain.
Science, 288:107-112, 2000

PubMed Abstract: The crystal structure of a 70-kilodalton ribonucleoprotein complex from the central domain of the Thermus thermophilus 30S ribosomal subunit was solved at 2.6 angstrom resolution. The complex consists of a 104-nucleotide RNA fragment composed of two three-helix junctions that lie at the end of a central helix, and the ribosomal proteins S15, S6, and S18. S15 binds the ribosomal RNA early in the assembly of the 30S ribosomal subunit, stabilizing a conformational reorganization of the two three-helix junctions that creates the RNA fold necessary for subsequent binding of S6 and S18. The structure of the complex demonstrates the central role of S15-induced reorganization of central domain RNA for the subsequent steps of ribosome assembly.

PubMed: 10753109
DOI: 10.1126/science.288.5463.107

実験手法

X-RAY DIFFRACTION (2.6 Å)