1G1R

Crystal structure of P-selectin lectin/EGF domains complexed with SLeX

1G1R の概要

• エントリーDOI: 10.2210/pdb1g1r/pdb
• 関連するPDBエントリー: 1G1Q 1G1S 1G1T
• 分子名称: P-SELECTIN, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: lectin, egf, adhesion molecule, slex, immune system, membrane protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P16109
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 79425.92

構造登録者

Somers, W.S.,Camphausen, R.T. (登録日: 2000-10-13, 公開日: 2001-10-13, 最終更新日: 2020-07-29)

• 主引用文献: Somers, W.S.,Tang, J.,Shaw, G.D.,Camphausen, R.T.; Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1.; Cell(Cambridge,Mass.), 103:467-479, 2000; PubMed: 11081633; DOI: 10.1016/S0092-8674(00)00138-0

実験手法

X-RAY DIFFRACTION (3.4 Å)