1G0V

THE STRUCTURE OF PROTEINASE A COMPLEXED WITH A IA3 MUTANT, MVV

Summary for 1G0V

• Entry DOI: 10.2210/pdb1g0v/pdb
• Related: 1DP5 1DPJ
• Descriptor: PROTEINASE A, PROTEASE A INHIBITOR 3, beta-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: proteinase a, mvv, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Saccharomyces cerevisiae (baker's yeast)
• Total number of polymer chains: 2
• Total formula weight: 40967.94

Authors

Phylip, L.H.,Lees, W.,Brownsey, B.G.,Bur, D.,Dunn, B.M.,Winther, J.,Gustchina, A.,Li, M.,Copeland, T.,Wlodawer, A.,Kay, J. (deposition date: 2000-10-09, release date: 2001-04-21, Last modification date: 2021-11-03)

• Primary citation: Phylip, L.H.,Lees, W.E.,Brownsey, B.G.,Bur, D.,Dunn, B.M.,Winther, J.R.,Gustchina, A.,Li, M.,Copeland, T.,Wlodawer, A.,Kay, J.; The potency and specificity of the interaction between the IA3 inhibitor and its target aspartic proteinase from Saccharomyces cerevisiae.; J.Biol.Chem., 276:2023-2030, 2001; PubMed: 11042188; DOI: 10.1074/jbc.M008520200

Experimental method

X-RAY DIFFRACTION (2 Å)