1FYX

CRYSTAL STRUCTURE OF P681H MUTANT OF TIR DOMAIN OF HUMAN TLR2

Summary for 1FYX

Related1FYV 1FYW
DescriptorTOLL-LIKE RECEPTOR 2 (1 entity in total)
Functional Keywordsbeta-alpha-beta fold, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationMembrane ; Single-pass type I membrane protein  O60603
Total number of polymer chains1
Total molecular weight18355.54
Authors
Xu, Y.,Tao, X.,Shen, B.,Horng, T.,Medzhitov, R.,Manley, J.L.,Tong, L. (deposition date: 2000-10-03, release date: 2000-11-22, Last modification date: 2018-01-31)
Primary citation
Xu, Y.,Tao, X.,Shen, B.,Horng, T.,Medzhitov, R.,Manley, J.L.,Tong, L.
Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.
Nature, 408:111-115, 2000
PubMed: 11081518 (PDB entries with the same primary citation)
DOI: 10.1038/35047056
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers217.0%3.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1fyx
no rotation
Molmil generated image of 1fyx
rotated about x axis by 90°
Molmil generated image of 1fyx
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 1fyx
no rotation
Molmil generated image of 1fyx
rotated about x axis by 90°
Molmil generated image of 1fyx
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (1fyx.pdb1.gz [27.25 KB])
Coordinate files for Biological unit (1fyx.pdb2.gz [52.79 KB])