1FYW
CRYSTAL STRUCTURE OF THE TIR DOMAIN OF HUMAN TLR2
Summary for 1FYW
Entry DOI | 10.2210/pdb1fyw/pdb |
Descriptor | TOLL-LIKE RECEPTOR 2 (1 entity in total) |
Functional Keywords | beta-alpha-beta fold parallel beta sheet, structural genomics, psi, protein structure initiative, northeast structural genomics consortium, nesg, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Membrane ; Single-pass type I membrane protein : O60603 |
Total number of polymer chains | 1 |
Total formula weight | 18455.20 |
Authors | Xu, Y.,Tao, X.,Shen, B.,Horng, T.,Medzhitov, R.,Manley, J.L.,Tong, L.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2000-10-03, release date: 2000-11-22, Last modification date: 2018-01-31) |
Primary citation | Xu, Y.,Tao, X.,Shen, B.,Horng, T.,Medzhitov, R.,Manley, J.L.,Tong, L. Structural basis for signal transduction by the Toll/interleukin-1 receptor domains. Nature, 408:111-115, 2000 Cited by PubMed: 11081518DOI: 10.1038/35047056 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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