1FY8

CRYSTAL STRUCTURE OF THE DELTAILE16VAL17 RAT ANIONIC TRYPSINOGEN-BPTI COMPLEX

Summary for 1FY8

• Entry DOI: 10.2210/pdb1fy8/pdb
• Related: 1F5R 1F7Z 3TGK
• Descriptor: TRYPSIN II, ANIONIC, PANCREATIC TRYPSIN INHIBITOR, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: protein-protein complex, protease-inhibitor complex, beta barrel, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Rattus rattus (black rat); More
• Cellular location: Secreted, extracellular space: P00763; Secreted: P00974
• Total number of polymer chains: 2
• Total formula weight: 31591.53

Authors

Pasternak, A.,White, A.,Jeffery, C.J.,Ringe, D.,Hedstrom, L. (deposition date: 2000-09-28, release date: 2000-11-08, Last modification date: 2017-10-04)

• Primary citation: Pasternak, A.,White, A.,Jeffery, C.J.,Medina, N.,Cahoon, M.,Ringe, D.,Hedstrom, L.; The energetic cost of induced fit catalysis: Crystal structures of trypsinogen mutants with enhanced activity and inhibitor affinity.; Protein Sci., 10:1331-1342, 2001; PubMed: 11420435; DOI: 10.1110/ps.44101

Experimental method

X-RAY DIFFRACTION (1.7 Å)