1FXY
COAGULATION FACTOR XA-TRYPSIN CHIMERA INHIBITED WITH D-PHE-PRO-ARG-CHLOROMETHYLKETONE
Summary for 1FXY
Entry DOI | 10.2210/pdb1fxy/pdb |
Related PRD ID | PRD_000020 |
Descriptor | COAGULATION FACTOR XA-TRYPSIN CHIMERA, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide (3 entities in total) |
Functional Keywords | chimera, protease, chloromethylketone, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space: P07477 |
Total number of polymer chains | 1 |
Total formula weight | 25122.80 |
Authors | Hopfner, K.P.,Kopetzki, E.,Kresse, G.-B.,Huber, R.,Bode, W.,Engh, R.A. (deposition date: 1998-04-22, release date: 1998-06-17, Last modification date: 2013-02-27) |
Primary citation | Hopfner, K.P.,Kopetzki, E.,Kresse, G.B.,Bode, W.,Huber, R.,Engh, R.A. New enzyme lineages by subdomain shuffling. Proc.Natl.Acad.Sci.USA, 95:9813-9818, 1998 Cited by PubMed: 9707558DOI: 10.1073/pnas.95.17.9813 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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