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1FWL

CRYSTAL STRUCTURE OF HOMOSERINE KINASE

Summary for 1FWL
Entry DOI10.2210/pdb1fwl/pdb
Related1FWK
DescriptorHOMOSERINE KINASE (2 entities in total)
Functional Keywordskinase, transferase
Biological sourceMethanocaldococcus jannaschii
Cellular locationCytoplasm (Potential): Q58504
Total number of polymer chains4
Total formula weight129197.48
Authors
Zhou, T.,Daugherty, M.,Grishin, N.V.,Osterman, A.L.,Zhang, H. (deposition date: 2000-09-22, release date: 2000-12-20, Last modification date: 2024-02-07)
Primary citationZhou, T.,Daugherty, M.,Grishin, N.V.,Osterman, A.L.,Zhang, H.
Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily.
Structure Fold.Des., 8:1247-1257, 2000
Cited by
PubMed Abstract: Homoserine kinase (HSK) catalyzes an important step in the threonine biosynthesis pathway. It belongs to a large yet unique class of small metabolite kinases, the GHMP kinase superfamily. Members in the GHMP superfamily participate in several essential metabolic pathways, such as amino acid biosynthesis, galactose metabolism, and the mevalonate pathway.
PubMed: 11188689
DOI: 10.1016/S0969-2126(00)00533-5
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.25 Å)
Structure validation

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건을2025-07-30부터공개중

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