1FV1

STRUCTURAL BASIS FOR THE BINDING OF AN IMMUNODOMINANT PEPTIDE FROM MYELIN BASIC PROTEIN IN DIFFERENT REGISTERS BY TWO HLA-DR2 ALLELES

Summary for 1FV1

DescriptorMAJOR HISTOCOMPATIBILITY COMPLEX ALPHA CHAIN, MAJOR HISTOCOMPATIBILITY COMPLEX BETA CHAIN, MYELIN BASIC PROTEIN, ... (6 entities in total)
Functional Keywordsmhc class ii dr2a, immune system
Biological sourceHomo sapiens (human)
More
Cellular locationCell membrane; Single-pass type I membrane protein P01903 Q30154
Myelin membrane; Peripheral membrane protein; Cytoplasmic side P02686
Total number of polymer chains6
Total molecular weight91662.43
Authors
Li, H.,Mariuzza, A.R.,Li, Y.,Martin, R. (deposition date: 2000-09-18, release date: 2000-09-27, Last modification date: 2011-07-13)
Primary citation
Li, Y.,Li, H.,Martin, R.,Mariuzza, R.A.
Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins.
J.Mol.Biol., 304:177-188, 2000
PubMed: 11080454 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.2000.4198
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers151.2%3.0%5.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution