1FUN

SUPEROXIDE DISMUTASE MUTANT WITH LYS 136 REPLACED BY GLU, CYS 6 REPLACED BY ALA AND CYS 111 REPLACED BY SER (K136E, C6A, C111S)

1FUN の概要

• エントリーDOI: 10.2210/pdb1fun/pdb
• 分子名称: SUPEROXIDE DISMUTASE, COPPER (II) ION, ZINC ION, ... (5 entities in total)
• 機能のキーワード: oxidoreductase, superoxide acceptor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P00441
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 159179.24

構造登録者

Lo, T.P.,Tainer, J.A.,Getzoff, E.D. (登録日: 1998-07-23, 公開日: 1999-07-23, 最終更新日: 2021-11-03)

• 主引用文献: Fisher, C.L.,Cabelli, D.E.,Hallewell, R.A.,Beroza, P.,Lo, T.P.,Getzoff, E.D.,Tainer, J.A.; Computational, pulse-radiolytic, and structural investigations of lysine-136 and its role in the electrostatic triad of human Cu,Zn superoxide dismutase.; Proteins, 29:103-112, 1997; PubMed: 9294870; DOI: 10.1002/(SICI)1097-0134(199709)29:1<103::AID-PROT8>3.0.CO;2-G

実験手法

X-RAY DIFFRACTION (2.85 Å)