1FMQ

Cyclo-butyl-bis-furamidine complexed with dCGCGAATTCGCG

Summary for 1FMQ

• Entry DOI: 10.2210/pdb1fmq/pdb
• Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION, 2,5-BIS{[4-(N-CYCLOBUTYLDIAMINOMETHYL)PHENYL]}FURAN, ... (4 entities in total)
• Functional Keywords: dna-drug minor groove complex, dna
• Total number of polymer chains: 2
• Total formula weight: 7767.65

Authors

Simpson, I.J.,Lee, M.,Kumar, A.,Boykin, D.W.,Neidle, S. (deposition date: 2000-08-18, release date: 2000-09-11, Last modification date: 2024-02-07)

• Primary citation: Simpson, I.J.,Lee, M.,Kumar, A.,Boykin, D.W.,Neidle, S.; DNA minor groove interactions and the biological activity of 2,5-bis-[4-(N-alkylamidino)phenyl] furans; Bioorg.Med.Chem.Lett., 10:2593-2597, 2000; PubMed: 11128631; DOI: 10.1016/S0960-894X(00)00511-4

Experimental method

X-RAY DIFFRACTION (2 Å)