1FMO

CRYSTAL STRUCTURE OF A POLYHISTIDINE-TAGGED RECOMBINANT CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE COMPLEXED WITH THE PEPTIDE INHIBITOR PKI(5-24) AND ADENOSINE

1FMO の概要

• エントリーDOI: 10.2210/pdb1fmo/pdb
• 分子名称: CAMP-DEPENDENT PROTEIN KINASE, HEAT STABLE RABBIT SKELETAL MUSCLE INHIBITOR PROTEIN, ADENOSINE, ... (4 entities in total)
• 機能のキーワード: complex (phosphotransferase-inhibitor), phosphorylation, polyhistidine-tag, protein kinase, complex (phosphotransferase-inhibitor) complex, complex (phosphotransferase/inhibitor)
• 由来する生物種: Mus musculus (house mouse)
• 細胞内の位置: Cytoplasm (By similarity): P05132
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43150.97

構造登録者

Narayana, N.,Cox, S.,Shaltiel, S.,Taylor, S.S.,Xuong, N.-H. (登録日: 1997-07-08, 公開日: 1998-01-14, 最終更新日: 2023-08-09)

• 主引用文献: Narayana, N.,Cox, S.,Shaltiel, S.,Taylor, S.S.,Xuong, N.; Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of cAMP-dependent protein kinase complexed with the peptide inhibitor PKI(5-24) and adenosine.; Biochemistry, 36:4438-4448, 1997; PubMed: 9109651; DOI: 10.1021/bi961947+

実験手法

X-RAY DIFFRACTION (2.2 Å)