1FGJ

X-RAY STRUCTURE OF HYDROXYLAMINE OXIDOREDUCTASE

1FGJ の概要

• エントリーDOI: 10.2210/pdb1fgj/pdb
• 分子名称: HYDROXYLAMINE OXIDOREDUCTASE, PROTOPORPHYRIN IX CONTAINING FE, HEME C (3 entities in total)
• 機能のキーワード: oxidoreductase, nitrification
• 由来する生物種: Nitrosomonas europaea
• 細胞内の位置: Periplasm: Q50925
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 133340.75

構造登録者

Tanaka, N.,Igarashi, N.,Moriyama, H. (登録日: 1997-03-03, 公開日: 1998-03-04, 最終更新日: 2024-11-13)

主引用文献

Igarashi, N.,Moriyama, H.,Fujiwara, T.,Fukumori, Y.,Tanaka, N.
The 2.8 A structure of hydroxylamine oxidoreductase from a nitrifying chemoautotrophic bacterium, Nitrosomonas europaea.
Nat.Struct.Biol., 4:276-284, 1997

PubMed Abstract: The 2.8 A crystal structure of hydroxylamine oxidoreductase of a nitrifying chemoautotrophic bacterium, Nitrosomonas europaea, is described. Twenty-four haems lie in the centre bottom of the trimeric molecule, localized in four clusters within each monomer. The haem clusters within the trimer are aligned to form a ring that has inlet and outlet sites. The inlet is occupied by a novel haem, P460, and there are two possible outlet sites per monomer formed by paired haems lying within a cavity or cleft on the protein surface. The structure suggests pathways by which electron transfer may occur through the precisely arranged haems and provides a framework for the interpretation of previous and future biochemical and genetic observations.

PubMed: 9095195
DOI: 10.1038/nsb0497-276

実験手法

X-RAY DIFFRACTION (2.8 Å)