1FCD

THE STRUCTURE OF FLAVOCYTOCHROME C SULFIDE DEHYDROGENASE FROM A PURPLE PHOTOTROPHIC BACTERIUM CHROMATIUM VINOSUM AT 2.5 ANGSTROMS RESOLUTION

1FCD の概要

• エントリーDOI: 10.2210/pdb1fcd/pdb
• 分子名称: FLAVOCYTOCHROME C SULFIDE DEHYDROGENASE (FLAVIN-BINDING SUBUNIT), FLAVOCYTOCHROME C SULFIDE DEHYDROGENASE (CYTOCHROME SUBUNIT), FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
• 機能のキーワード: electron transport(flavocytochrome)
• 由来する生物種: Allochromatium vinosum; 詳細
• 細胞内の位置: Periplasm: Q06530 Q06529
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 128196.83

構造登録者

Chen, Z.W.,Koh, M.,Van Driessche, G.,Van Beeumen, J.J.,Bartsch, R.G.,Meyer, T.E.,Cusanovich, M.A.,Mathews, F.S. (登録日: 1994-08-18, 公開日: 1994-11-01, 最終更新日: 2024-10-09)

主引用文献

Chen, Z.W.,Koh, M.,Van Driessche, G.,Van Beeumen, J.J.,Bartsch, R.G.,Meyer, T.E.,Cusanovich, M.A.,Mathews, F.S.
The structure of flavocytochrome c sulfide dehydrogenase from a purple phototrophic bacterium.
Science, 266:430-432, 1994

PubMed Abstract: The structure of the heterodimeric flavocytochrome c sulfide dehydrogenase from Chromatium vinosum was determined at a resolution of 2.53 angstroms. It contains a glutathione reductase-like flavin-binding subunit and a diheme cytochrome subunit. The diheme cytochrome folds as two domains, each resembling mitochondrial cytochrome c, and has an unusual interpropionic acid linkage joining the two heme groups in the interior of the subunit. The active site of the flavoprotein subunit contains a catalytically important disulfide bridge located above the pyrimidine portion of the flavin ring. A tryptophan, threonine, or tyrosine side chain may provide a partial conduit for electron transfer to one of the heme groups located 10 angstroms from the flavin.

PubMed: 7939681

実験手法

X-RAY DIFFRACTION (2.53 Å)