1F8E

Native Influenza Neuraminidase in Complex with 4,9-diamino-2-deoxy-2,3-dehydro-N-acetyl-neuraminic Acid

1F8E の概要

• エントリーDOI: 10.2210/pdb1f8e/pdb
• 関連するPDBエントリー: 1F8B 1F8C 1F8E 7NN9
• 分子名称: NEURAMINIDASE, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: neuraminidase, hydrolase, influenza protein, glycosylated protein, dana, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Influenza A virus (A/tern/Australia/G70C/1975(H11N9))
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45991.94

構造登録者

Smith, B.J.,Colman, P.M.,Von Itzstein, M.,Danylec, B.,Varghese, J.N. (登録日: 2000-06-30, 公開日: 2001-04-11, 最終更新日: 2020-07-29)

• 主引用文献: Smith, B.J.,Colman, P.M.,Von Itzstein, M.,Danylec, B.,Varghese, J.N.; Analysis of inhibitor binding in influenza virus neuraminidase.; Protein Sci., 10:689-696, 2001; PubMed: 11274459; DOI: 10.1110/ps.41801

実験手法

X-RAY DIFFRACTION (1.4 Å)