1F7Z

RAT TRYPSINOGEN K15A COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR

Summary for 1F7Z

• Entry DOI: 10.2210/pdb1f7z/pdb
• Related: 1F5R 3TGI
• Descriptor: TRYPSIN II, ANIONIC, PANCREATIC TRYPSIN INHIBITOR, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: serine protease, trypsin precursor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Rattus norvegicus (Norway rat); More
• Cellular location: Secreted, extracellular space: P00763; Secreted: P00974
• Total number of polymer chains: 2
• Total formula weight: 32459.56

Authors

Pasternak, A.,White, A.,Jeffery, C.J.,Medina, N.,Cahoon, M.,Ringe, D.,Hedstrom, L. (deposition date: 2000-06-28, release date: 2001-07-04, Last modification date: 2021-11-03)

• Primary citation: Pasternak, A.,White, A.,Jeffery, C.J.,Medina, N.,Cahoon, M.,Ringe, D.,Hedstrom, L.; The energetic cost of induced fit catalysis: Crystal structures of trypsinogen mutants with enhanced activity and inhibitor affinity.; Protein Sci., 10:1331-1342, 2001; PubMed: 11420435; DOI: 10.1110/ps.44101

Experimental method

X-RAY DIFFRACTION (1.55 Å)