1F4M

P3(2) CRYSTAL STRUCTURE OF ALA2ILE2-6, A VERSION OF ROP WITH A REPACKED HYDROPHOBIC CORE AND A NEW FOLD.

1F4M の概要

• エントリーDOI: 10.2210/pdb1f4m/pdb
• 関連するPDBエントリー: 1B6Q 1F4N 1GTO 1NKD 1ROP 1RPO 1RPR
• 分子名称: ROP ALA2ILE2-6, CALCIUM ION (3 entities in total)
• 機能のキーワード: rop, dimer, homodimer, helix-turn-helix, transcription regulation, hydrophobic core packing, thermodynamic stability, transcription
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 42563.07

構造登録者

Willis, M.A.,Bishop, B.,Regan, L.,Brunger, A.T. (登録日: 2000-06-08, 公開日: 2001-01-10, 最終更新日: 2024-02-07)

主引用文献

Willis, M.A.,Bishop, B.,Regan, L.,Brunger, A.T.
Dramatic structural and thermodynamic consequences of repacking a protein's hydrophobic core.
Structure Fold.Des., 8:1319-1328, 2000

PubMed Abstract: Rop is an RNA binding, dimeric, four-helix bundle protein with a well-defined, regular hydrophobic core ideally suited for redesign studies. A family of Rop variants in which the hydrophobic core was systematically redesigned has previously been created and characterized.

PubMed: 11188696
DOI: 10.1016/S0969-2126(00)00544-X

実験手法

X-RAY DIFFRACTION (2.25 Å)