1EYE

1.7 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTEROATE SYNTHASE (DHPS) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH 6-HYDROXYMETHYLPTERIN MONOPHOSPHATE

Summary for 1EYE

Related1aj0 1ajz 1aj2 1ad1 1ad4
DescriptorDIHYDROPTEROATE SYNTHASE I, MAGNESIUM ION, PTERIN-6-YL-METHYL-MONOPHOSPHATE, ... (4 entities in total)
Functional Keywordsalpha-beta barrel, transferase
Biological sourceMycobacterium tuberculosis H37Rv
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Total number of polymer chains1
Total molecular weight29170.36
Authors
Baca, A.M.,Sirawaraporn, R.,Turley, S.,Sirawaraporn, W.,Hol, W.G.J. (deposition date: 2000-05-05, release date: 2000-10-11, Last modification date: 2018-02-07)
Primary citation
Baca, A.M.,Sirawaraporn, R.,Turley, S.,Sirawaraporn, W.,Hol, W.G.
Crystal structure of Mycobacterium tuberculosis 7,8-dihydropteroate synthase in complex with pterin monophosphate: new insight into the enzymatic mechanism and sulfa-drug action.
J.Mol.Biol., 302:1193-1212, 2000
PubMed: 11007651 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.2000.4094
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.7 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers150.4%8.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report