1EYE

1.7 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTEROATE SYNTHASE (DHPS) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH 6-HYDROXYMETHYLPTERIN MONOPHOSPHATE

1EYE の概要

• エントリーDOI: 10.2210/pdb1eye/pdb
• 関連するPDBエントリー: 1ad1 1ad4 1aj0 1aj2 1ajz
• 分子名称: DIHYDROPTEROATE SYNTHASE I, MAGNESIUM ION, PTERIN-6-YL-METHYL-MONOPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: alpha-beta barrel, transferase
• 由来する生物種: Mycobacterium tuberculosis H37Rv
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29170.36

構造登録者

Baca, A.M.,Sirawaraporn, R.,Turley, S.,Sirawaraporn, W.,Hol, W.G.J. (登録日: 2000-05-05, 公開日: 2000-10-11, 最終更新日: 2024-03-13)

• 主引用文献: Baca, A.M.,Sirawaraporn, R.,Turley, S.,Sirawaraporn, W.,Hol, W.G.; Crystal structure of Mycobacterium tuberculosis 7,8-dihydropteroate synthase in complex with pterin monophosphate: new insight into the enzymatic mechanism and sulfa-drug action.; J.Mol.Biol., 302:1193-1212, 2000; PubMed: 11007651; DOI: 10.1006/jmbi.2000.4094

実験手法

X-RAY DIFFRACTION (1.7 Å)