1EY3

STRUCTURE OF ENOYL-COA HYDRATASE COMPLEXED WITH THE SUBSTRATE DAC-COA

Summary for 1EY3

Entry DOI	10.2210/pdb1ey3/pdb
Descriptor	ENOYL-COA HYDRATASE, 4-(N,N-DIMETHYLAMINO)CINNAMOYL-COA (3 entities in total)
Functional Keywords	beta-oxidation, crotonase, enoyl-coa hydratase, fatty acid metabolism, beta-elimination, syn-addition, concerted reaction, lyase
Biological source	Rattus norvegicus (Norway rat)
Cellular location	Mitochondrion matrix: P14604
Total number of polymer chains	6
Total formula weight	174120.18
Authors	Bahnson, B.J.,Anderson, V.E.,Petsko, G.A. (deposition date: 2000-05-05, release date: 2002-02-27, Last modification date: 2024-03-13)
Primary citation	Bahnson, B.J.,Anderson, V.E.,Petsko, G.A. Structural mechanism of enoyl-CoA hydratase: three atoms from a single water are added in either an E1cb stepwise or concerted fashion. Biochemistry, 41:2621-2629, 2002 Cited by PubMed: 11851409 DOI: 10.1021/bi015844p PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation