1EXZ
STRUCTURE OF STEM CELL FACTOR
Summary for 1EXZ
Entry DOI | 10.2210/pdb1exz/pdb |
Descriptor | STEM CELL FACTOR, CALCIUM ION, SAMARIUM (III) ION, ... (5 entities in total) |
Functional Keywords | scf, hormone-growth factor complex, hormone/growth factor |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein (By similarity). Soluble KIT ligand: Secreted: P21583 |
Total number of polymer chains | 4 |
Total formula weight | 64832.96 |
Authors | Zhang, Z.,Zhang, R.,Joachimiak, A.,Schlessinger, J.,Kong, X. (deposition date: 2000-05-05, release date: 2000-07-06, Last modification date: 2011-07-13) |
Primary citation | Zhang, Z.,Zhang, R.,Joachimiak, A.,Schlessinger, J.,Kong, X.P. Crystal structure of human stem cell factor: implication for stem cell factor receptor dimerization and activation. Proc.Natl.Acad.Sci.USA, 97:7732-7737, 2000 Cited by PubMed: 10884405DOI: 10.1073/pnas.97.14.7732 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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