1EOT

SOLUTION NMR STRUCTURE OF EOTAXIN, MINIMIZED AVERAGE STRUCTURE

Summary for 1EOT

• Entry DOI: 10.2210/pdb1eot/pdb
• NMR Information: BMRB: 4155
• Descriptor: EOTAXIN (1 entity in total)
• Functional Keywords: cytokine, chemokine, protein synthesis, eotaxin, solution structure, ccr3, eosinophil
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 8380.94

Authors

Crump, M.P.,Rajarathnam, K.,Sykes, B.D. (deposition date: 1998-06-17, release date: 1999-01-13, Last modification date: 2024-11-20)

Primary citation

Crump, M.P.,Rajarathnam, K.,Kim, K.S.,Clark-Lewis, I.,Sykes, B.D.
Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation.
J.Biol.Chem., 273:22471-22479, 1998

PubMed Abstract: The solution structure of the CCR3-specific chemokine, eotaxin, has been determined by NMR spectroscopy. The quaternary structure of eotaxin was investigated by ultracentrifugation and NMR, and it was found to be in equilibrium between monomer and dimer under a wide range of conditions. At pH PubMed: 9712872
DOI: 10.1074/jbc.273.35.22471

Experimental method

SOLUTION NMR