1EI2

STRUCTURAL BASIS FOR RECOGNITION OF THE RNA MAJOR GROOVE IN THE TAU EXON 10 SPLICING REGULATORY ELEMENT BY AMINOGLYCOSIDE ANTIBIOTICS

Summary for 1EI2

• Entry DOI: 10.2210/pdb1ei2/pdb
• Related: 1qc8
• Descriptor: TAU EXON 10 SRE RNA, NEOMYCIN (2 entities in total)
• Functional Keywords: rna, tau, frontotemporal dementia ftdp-17, intronic mutations, aminoglycoside, rna major groove recognition
• Total number of polymer chains: 1
• Total formula weight: 8605.42

Authors

Varani, L.,Spillantini, M.G.,Goedert, M.,Varani, G. (deposition date: 2000-02-23, release date: 2000-03-06, Last modification date: 2017-02-01)

• Primary citation: Varani, L.,Spillantini, M.G.,Goedert, M.,Varani, G.; Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics.; Nucleic Acids Res., 28:710-719, 2000; PubMed: 10637322; DOI: 10.1093/nar/28.3.710

Experimental method

SOLUTION NMR