1EFU

ELONGATION FACTOR COMPLEX EF-TU/EF-TS FROM ESCHERICHIA COLI

1EFU の概要

• エントリーDOI: 10.2210/pdb1efu/pdb
• 分子名称: ELONGATION FACTOR TU, ELONGATION FACTOR TS (3 entities in total)
• 機能のキーワード: elongation factor, complex (two elongation factors)
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 145125.93

構造登録者

Kawashima, T.,Berthet-Colominas, C.,Wulff, M.,Cusack, S.,Leberman, R. (登録日: 1996-07-09, 公開日: 1997-01-11, 最終更新日: 2024-02-07)

主引用文献

Kawashima, T.,Berthet-Colominas, C.,Wulff, M.,Cusack, S.,Leberman, R.
The structure of the Escherichia coli EF-Tu.EF-Ts complex at 2.5 A resolution.
Nature, 379:511-518, 1996

PubMed Abstract: The crystal structure of the EF-Tu.EF-Ts complex from Escherichia coli has been determined to a resolution of 2.5 A. The complex contains two subunits of each of the elongation factors. The two EF-Ts molecules form a tight dimer, but there is little contact between the two EF-Tu molecules. The interaction of EF-Ts with EF-Tu results principally in the disruption of the Mg2+ ion binding site, thereby reducing the affinity of EF-Tu for guanine nucleotides.

PubMed: 8596629
DOI: 10.1038/379511a0

実験手法

X-RAY DIFFRACTION (2.5 Å)