1EEY

Crystal Structure Determination Of HLA A2 Complexed to Peptide GP2 with the substitution (I2L/V5L/L9V)

Summary for 1EEY

• Entry DOI: 10.2210/pdb1eey/pdb
• Related: 1EEZ 1QR1
• Descriptor: HLA-A2.1 MHC CLASS I (HEAVY CHAIN), BETA-2-MICROGLOBULIN (LIGHT CHAIN), GP2 PEPTIDE, ... (4 entities in total)
• Functional Keywords: major histicompatibility complex, peptide binding, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01892; Secreted: P01884
• Total number of polymer chains: 6
• Total formula weight: 89235.35

Authors

Sharma, A.K.,Kuhns, J.J.,Collins, E.J. (deposition date: 2000-02-04, release date: 2003-06-10, Last modification date: 2022-12-21)

• Primary citation: Sharma, A.K.,Kuhns, J.J.,Yan, S.,Friedline, R.H.,Long, B.,Tisch, R.,Collins, E.J.; Class I major histocompatibility complex anchor substitutions alter the conformation of T cell receptor contacts.; J.Biol.Chem., 276:21443-21449, 2001; PubMed: 11287414; DOI: 10.1074/jbc.M010791200

Experimental method

X-RAY DIFFRACTION (2.25 Å)