1ECL
AMINO TERMINAL 67KDA DOMAIN OF ESCHERICHIA COLI DNA TOPOISOMERASE I (RESIDUES 2-590 OF MATURE PROTEIN) CLONING ARTIFACT ADDS TWO RESIDUES TO THE AMINO-TERMINUS WHICH WERE NOT OBSERVED IN THE EXPERIMENTAL ELECTRON DENSITY (GLY-2, SER-1).
Summary for 1ECL
| Entry DOI | 10.2210/pdb1ecl/pdb |
| Descriptor | ESCHERICHIA COLI TOPOISOMERASE I (2 entities in total) |
| Functional Keywords | bacterial type i, dna cleavage, strand passage, topoisomerase |
| Biological source | Escherichia coli |
| Total number of polymer chains | 1 |
| Total formula weight | 67326.30 |
| Authors | Lima, C.D.,Wang, J.C.,Mondragon, A. (deposition date: 1995-05-05, release date: 1995-07-31, Last modification date: 2024-02-07) |
| Primary citation | Lima, C.D.,Wang, J.C.,Mondragon, A. Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I. Nature, 367:138-146, 1994 Cited by PubMed: 8114910DOI: 10.1038/367138a0 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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