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1EAW

Crystal structure of the MTSP1 (matriptase)-BPTI (aprotinin) complex

Summary for 1EAW
Entry DOI10.2210/pdb1eaw/pdb
Related1EAX
DescriptorSUPPRESSOR OF TUMORIGENICITY 14, PANCREATIC TRYPSIN INHIBITOR (3 entities in total)
Functional Keywordshydrolase/inhibitor, complex (serine protease inhibitor), serine proteinase, matrix degradation, inhibitor, glycoprote hydrolase, hydrolase-inhibitor complex
Biological sourceHOMO SAPIENS (HUMAN)
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Cellular locationMembrane ; Single-pass type II membrane protein : Q9Y5Y6
Secreted: P00974
Total number of polymer chains4
Total formula weight65982.65
Authors
Friedrich, R.,Bode, W. (deposition date: 2001-07-17, release date: 2002-01-28, Last modification date: 2023-12-13)
Primary citationFriedrich, R.,Fuentes-Prior, P.,Ong, E.,Coombs, G.,Hunter, M.,Oehler, R.,Pierson, D.,Gonzalez, R.,Huber, R.,Bode, W.,Madison, E.L.
Catalytic Domain Structures of Mt-Sp1/Matriptase, a Matrix-Degrading Transmembrane Serine Proteinase.
J.Biol.Chem., 277:2160-, 2002
Cited by
PubMed: 11696548
DOI: 10.1074/JBC.M109830200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.93 Å)
Structure validation

217705

數據於2024-03-27公開中

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