1EAL

NMR STUDY OF ILEAL LIPID BINDING PROTEIN

1EAL の概要

• エントリーDOI: 10.2210/pdb1eal/pdb
• 分子名称: ILEAL LIPID BINDING PROTEIN (1 entity in total)
• 機能のキーワード: intracellular lipid binding protein, bile acid binding, ileal epithelium, fatty acid binding protein
• 由来する生物種: Sus scrofa (pig)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14093.88

構造登録者

Luecke, C.,Zhang, F.,Rueterjans, H.,Hamilton, J.A.,Sacchettini, J.C. (登録日: 1996-08-28, 公開日: 1997-01-22, 最終更新日: 2024-05-22)

主引用文献

Lucke, C.,Zhang, F.,Ruterjans, H.,Hamilton, J.A.,Sacchettini, J.C.
Flexibility is a likely determinant of binding specificity in the case of ileal lipid binding protein.
Structure, 4:785-800, 1996

PubMed Abstract: The family of lipid binding proteins (LBPs) includes a large number of fatty acid binding proteins (FABPs) but only two proteins (ileal lipid binding protein, ILBP, and liver fatty acid binding protein) that can bind both fatty acids and bile acids. Bile acid transport is medically and pharmacologically important, but is poorly understood. To understand the binding properties of ILBP, we studied its solution structure with and without bound lipids and compared these with known structures of FABPs.

PubMed: 8805562
DOI: 10.1016/S0969-2126(96)00086-X

実験手法

SOLUTION NMR