1E74

NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT R11E

Summary for 1E74

Related1E75 1E76 1IM1 1IMI 1CNL
DescriptorALPHA-CONOTOXIN IM1(R11E) (1 entity in total)
Functional Keywordspeptide toxin, neurotoxin, neuronal nicotinic acetylcholine receptor antagonist, alpha-conotoxin, nmr solution structure
Biological sourceCONUS IMPERIALIS
Cellular locationSecreted  P50983
Total number of polymer chains1
Total molecular weight1328.52
Authors
Rogers, J.P.,Luginbuhl, P.,Pemberton, K.,Harty, P.,Wemmer, D.E.,Stevens, R.C. (deposition date: 2000-08-24, release date: 2000-12-27, Last modification date: 2017-06-14)
Primary citation
Rogers, J.P.,Luginbuhl, P.,Pemberton, K.,Harty, P.,Wemmer, D.E.,Stevens, R.C.
Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist
J.Mol.Biol., 304:911-, 2000
PubMed: 11124036 (PDB entries with the same primary citation)
DOI: 10.1006/JMBI.2000.4247
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers06.8%19.5%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures