1E6I

Bromodomain from GCN5 complexed with acetylated H4 peptide

Summary for 1E6I

• Entry DOI: 10.2210/pdb1e6i/pdb
• Related: 1YGH
• Descriptor: TRANSCRIPTIONAL ACTIVATOR GCN5, HISTONE H4 (3 entities in total)
• Functional Keywords: gene regulation, histone binding, n-acetyl lysine
• Biological source: SACCHAROMYCES CEREVISIAE; More
• Cellular location: Nucleus: Q03330 P02309
• Total number of polymer chains: 2
• Total formula weight: 16243.47

Authors

Owen, D.J.,Travers, A.A.,Evans, P.R. (deposition date: 2000-08-18, release date: 2000-11-24, Last modification date: 2012-11-28)

• Primary citation: Owen, D.J.,Ornaghi, P.,Yang, J.C.,Lowe, N.,Evans, P.R.,Ballario, P.,Neuhaus, D.,Filetici, P.,Travers, A.A.; The Structural Basis for the Recognition of Acetylated Histone H4 by the Bromodomain of Histone Acetyltransferase Gcn5P; Embo J., 19:6141-, 2000; PubMed: 11080160; DOI: 10.1093/EMBOJ/19.22.6141

Experimental method

X-RAY DIFFRACTION (1.87 Å)