1E1A

Crystal structure of DFPase from Loligo vulgaris

1E1A の概要

• エントリーDOI: 10.2210/pdb1e1a/pdb
• 分子名称: DIISOPROPYLFLUOROPHOSPHATASE, CALCIUM ION (3 entities in total)
• 機能のキーワード: phosphotriesterase, calcium-binding site, phosphotriesterase (pte), selenometionine, beta-propeller
• 由来する生物種: LOLIGO VULGARIS (SQUID)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35200.87

構造登録者

Koepke, J.,Scharff, E.I.,Fritzsch, G.,Luecke, C.,Rueterjans, H. (登録日: 2000-04-28, 公開日: 2001-06-06, 最終更新日: 2024-05-08)

主引用文献

Scharff, E.I.,Koepke, J.,Fritzsch, G.,Luecke, C.,Rueterjans, H.
Crystal Structure of Diisopropylfluorophosphatase from Loligo Vulgaris
Structure, 9:493-, 2001

PubMed Abstract: Phosphotriesterases (PTE) are enzymes capable of detoxifying organophosphate-based chemical warfare agents by hydrolysis. One subclass of these enzymes comprises the family of diisopropylfluorophosphatases (DFPases). The DFPase reported here was originally isolated from squid head ganglion of Loligo vulgaris and can be characterized as squid-type DFPase. It is capable of hydrolyzing the organophosphates diisopropylfluorophosphate, soman, sarin, tabun, and cyclosarin.

PubMed: 11435114
DOI: 10.1016/S0969-2126(01)00610-4

実験手法

X-RAY DIFFRACTION (1.8 Å)