1DQN

CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH A TRANSITION STATE ANALOGUE

1DQN の概要

• エントリーDOI: 10.2210/pdb1dqn/pdb
• 関連するPDBエントリー: 1DQP
• 分子名称: GUANINE PHOSPHORIBOSYLTRANSFERASE, MAGNESIUM ION, PHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN-2-YLMETHYL] ESTER, ... (6 entities in total)
• 機能のキーワード: protein-inhibitor complex, mg ions, pyrophosphate, transition state analogue, transferase
• 由来する生物種: Giardia intestinalis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 53917.68

構造登録者

Shi, W.,Munagala, N.R.,Wang, C.C.,Li, C.M.,Tyler, P.C.,Furneaux, R.H.,Grubmeyer, C.,Schramm, V.L.,Almo, S.C. (登録日: 2000-01-04, 公開日: 2000-07-26, 最終更新日: 2024-02-07)

• 主引用文献: Shi, W.,Munagala, N.R.,Wang, C.C.,Li, C.M.,Tyler, P.C.,Furneaux, R.H.,Grubmeyer, C.,Schramm, V.L.,Almo, S.C.; Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).; Biochemistry, 39:6781-6790, 2000; PubMed: 10841757; DOI: 10.1021/bi000128t

実験手法

X-RAY DIFFRACTION (1.75 Å)