1DPG

GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES

Summary for 1DPG

• Entry DOI: 10.2210/pdb1dpg/pdb
• Descriptor: GLUCOSE 6-PHOSPHATE DEHYDROGENASE, PHOSPHATE ION (3 entities in total)
• Functional Keywords: oxidoreductase, nadp/nad, glucose metabolism, oxidoreductase (choh(d) - nad(p))
• Biological source: Leuconostoc mesenteroides
• Total number of polymer chains: 2
• Total formula weight: 109056.34

Authors

Adams, M.J.,Rowland, P.,Gover, S. (deposition date: 1995-12-04, release date: 1996-03-08, Last modification date: 2024-02-07)

Primary citation

Rowland, P.,Basak, A.K.,Gover, S.,Levy, H.R.,Adams, M.J.
The three-dimensional structure of glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides refined at 2.0 A resolution.
Structure, 2:1073-1087, 1994

PubMed Abstract: Glucose 6-phosphate dehydrogenase (G6PD) is the first enzyme of the pentose phosphate pathway. Normally the pathway is synthetic and NADP-dependent, but the Gram-positive bacterium Leuconostoc mesenteroides, which does not have a complete glycolytic pathway, also uses the oxidative enzymes of the pentose phosphate pathway for catabolic reactions, and selects either NAD or NADP depending on the demands for catabolic or anabolic metabolism.

PubMed: 7881907
DOI: 10.1016/S0969-2126(94)00110-3

Experimental method

X-RAY DIFFRACTION (2 Å)