1DNU

STRUCTURAL ANALYSES OF HUMAN MYELOPEROXIDASE-THIOCYANATE COMPLEX

1DNU の概要

• エントリーDOI: 10.2210/pdb1dnu/pdb
• 関連するPDBエントリー: 1CXP 1D2V 1D5L 1D7W 1DNW 1MHL 1MYP
• 分子名称: MYELOPEROXIDASE, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, THIOCYANATE ION, ... (10 entities in total)
• 機能のキーワード: oxidoreductase, peroxidase, inhibitor complex thiocyanate, halide peroxidation, neutrophil
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 135467.79

構造登録者

Blair-Johnson, M.,Fiedler, T.J.,Fenna, R.E. (登録日: 1999-12-16, 公開日: 2001-12-21, 最終更新日: 2020-07-29)

• 主引用文献: Blair-Johnson, M.,Fiedler, T.,Fenna, R.; Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution.; Biochemistry, 40:13990-13997, 2001; PubMed: 11705390; DOI: 10.1021/bi0111808

実験手法

X-RAY DIFFRACTION (1.85 Å)