1DLB

HELICAL INTERACTIONS IN THE HIV-1 GP41 CORE REVEALS STRUCTURAL BASIS FOR THE INHIBITORY ACTIVITY OF GP41 PEPTIDES

1DLB の概要

• エントリーDOI: 10.2210/pdb1dlb/pdb
• 分子名称: HIV-1 ENVELOPE GLYCOPROTEIN GP41 (2 entities in total)
• 機能のキーワード: gp41, hiv-1, membrane fusion, hiv-1 inhibition, virus/viral protein, viral protein
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• 細胞内の位置: Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P04578
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 7864.78

構造登録者

Shu, W.,Liu, J.,Ji, H.,Rading, L.,Jiang, S.,Lu, M. (登録日: 1999-12-09, 公開日: 1999-12-15, 最終更新日: 2024-02-07)

• 主引用文献: Shu, W.,Liu, J.,Ji, H.,Radigen, L.,Jiang, S.,Lu, M.; Helical interactions in the HIV-1 gp41 core reveal structural basis for the inhibitory activity of gp41 peptides.; Biochemistry, 39:1634-1642, 2000; PubMed: 10677212; DOI: 10.1021/bi9921687

実験手法

X-RAY DIFFRACTION (2 Å)