1DEV

CRYSTAL STRUCTURE OF SMAD2 MH2 DOMAIN BOUND TO THE SMAD-BINDING DOMAIN OF SARA

Summary for 1DEV

• Entry DOI: 10.2210/pdb1dev/pdb
• Descriptor: MAD (mothers against decapentaplegic, Drosophila) homolog 2, Smad anchor for receptor activation (2 entities in total)
• Functional Keywords: beta sheet, three-helix bundle, signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm : Q15796 O95405
• Total number of polymer chains: 4
• Total formula weight: 52817.75

Authors

Shi, Y.,Wu, G. (deposition date: 1999-11-15, release date: 2000-01-21, Last modification date: 2024-02-07)

• Primary citation: Wu, G.,Chen, Y.G.,Ozdamar, B.,Gyuricza, C.A.,Chong, P.A.,Wrana, J.L.,Massague, J.,Shi, Y.; Structural basis of Smad2 recognition by the Smad anchor for receptor activation.; Science, 287:92-97, 2000; PubMed: 10615055; DOI: 10.1126/science.287.5450.92

Experimental method

X-RAY DIFFRACTION (2.2 Å)