1DEO

RHAMNOGALACTURONAN ACETYLESTERASE FROM ASPERGILLUS ACULEATUS AT 1.55 A RESOLUTION WITH SO4 IN THE ACTIVE SITE

1DEO の概要

• エントリーDOI: 10.2210/pdb1deo/pdb
• 関連するPDBエントリー: 1DEX
• 分子名称: RHAMNOGALACTURONAN ACETYLESTERASE, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: sgnh hydrolase, hydrolase
• 由来する生物種: Aspergillus aculeatus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 26109.18

構造登録者

Molgaard, A.,Kauppinen, S.,Larsen, S. (登録日: 1999-11-15, 公開日: 2000-04-26, 最終更新日: 2024-11-20)

主引用文献

Molgaard, A.,Kauppinen, S.,Larsen, S.
Rhamnogalacturonan acetylesterase elucidates the structure and function of a new family of hydrolases.
Structure Fold.Des., 8:373-383, 2000

PubMed Abstract: The complex polysaccharide rhamnogalacturonan constitutes a major part of the hairy region of pectin. It can have different types of carbohydrate sidechains attached to the rhamnose residues in the backbone of alternating rhamnose and galacturonic acid residues; the galacturonic acid residues can be methylated or acetylated. Aspergillus aculeatus produces enzymes that are able to perform a synergistic degradation of rhamnogalacturonan. The deacetylation of the backbone by rhamnogalacturonan acetylesterase (RGAE) is an essential prerequisite for the subsequent action of the enzymes that cleave the glycosidic bonds.

PubMed: 10801485
DOI: 10.1016/S0969-2126(00)00118-0

実験手法

X-RAY DIFFRACTION (1.55 Å)