1D98

THE STRUCTURE OF AN OLIGO(DA).OLIGO(DT) TRACT AND ITS BIOLOGICAL IMPLICATIONS

Summary for 1D98

• Entry DOI: 10.2210/pdb1d98/pdb
• Descriptor: DNA (5'-D(*CP*GP*CP*AP*AP*AP*AP*AP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*TP*TP*TP*TP*TP*GP*CP*G)-3') (3 entities in total)
• Functional Keywords: b-dna, double helix, dna
• Total number of polymer chains: 2
• Total formula weight: 7324.81

Authors

Nelson, H.C.M.,Finch, J.T.,Luisi, B.F.,Klug, A. (deposition date: 1992-10-17, release date: 1993-04-15, Last modification date: 2024-02-07)

Primary citation

Nelson, H.C.,Finch, J.T.,Luisi, B.F.,Klug, A.
The structure of an oligo(dA).oligo(dT) tract and its biological implications.
Nature, 330:221-226, 1987

PubMed Abstract: Poly(dA).poly(dT) has unusual properties in that it cannot associate into nucleosomes and short, phased runs of it cause DNA bending. The crystal structure of a B-type DNA dodecamer containing a homopolymeric run of six A.T base pairs shows that this region possesses special structural features, including a system of bifurcated hydrogen bonds, which explains some of the properties of this simple homopolymer.

PubMed: 3670410
DOI: 10.1038/330221a0

Experimental method

X-RAY DIFFRACTION (2.5 Å)