1D85

STRUCTURAL CONSEQUENCES OF A CARCINOGENIC ALKYLATION LESION ON DNA: EFFECT OF O6-ETHYL-GUANINE ON THE MOLECULAR STRUCTURE OF D(CGC[E6G]AATTCGCG)-NETROPSIN COMPLEX

1D85 の概要

• エントリーDOI: 10.2210/pdb1d85/pdb
• 分子名称: DNA (5'-D(*CP*GP*CP*(G36)P*AP*AP*TP*TP*CP*GP*CP*G)-3'), NETROPSIN (3 entities in total)
• 機能のキーワード: b-dna, double helix, complexed with drug, modified, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 7813.35

構造登録者

Sriram, M.,Van Der Marel, G.A.,Roelen, H.L.P.F.,Van Boom, J.H.,Wang, A.H.-J. (登録日: 1992-08-24, 公開日: 1993-07-15, 最終更新日: 2024-02-07)

• 主引用文献: Sriram, M.,van der Marel, G.A.,Roelen, H.L.,van Boom, J.H.,Wang, A.H.; Structural consequences of a carcinogenic alkylation lesion on DNA: effect of O6-ethylguanine on the molecular structure of the d(CGC[e6G]AATTCGCG)-netropsin complex.; Biochemistry, 31:11823-11834, 1992; PubMed: 1332773; DOI: 10.1021/bi00162a022

実験手法

X-RAY DIFFRACTION (2.5 Å)