1D6W

STRUCTURE OF THROMBIN COMPLEXED WITH SELECTIVE NON-ELECTROPHILIC INHIBITORS HAVING CYCLOHEXYL MOIETIES AT P1

1D6W の概要

• エントリーDOI: 10.2210/pdb1d6w/pdb
• 分子名称: THROMBIN, DECAPEPTIDE INHIBITOR, SODIUM ION, ... (5 entities in total)
• 機能のキーワード: hydrolase, thrombin, thrombin inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted, extracellular space: P00734; Secreted: P28511
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 35030.97

構造登録者

Mochalkin, I.,Tulinsky, A. (登録日: 1999-10-15, 公開日: 2000-10-25, 最終更新日: 2017-10-04)

• 主引用文献: Krishnan, R.,Mochalkin, I.,Arni, R.,Tulinsky, A.; Structure of thrombin complexed with selective non-electrophilic inhibitors having cyclohexyl moieties at P1.; Acta Crystallogr.,Sect.D, 56:294-303, 2000; PubMed: 10713516; DOI: 10.1107/S0907444900000068

実験手法

X-RAY DIFFRACTION (2 Å)