1D6R
CRYSTAL STRUCTURE OF CANCER CHEMOPREVENTIVE BOWMAN-BIRK INHIBITOR IN TERNARY COMPLEX WITH BOVINE TRYPSIN AT 2.3 A RESOLUTION. STRUCTURAL BASIS OF JANUS-FACED SERINE PROTEASE INHIBITOR SPECIFICITY
Summary for 1D6R
Entry DOI | 10.2210/pdb1d6r/pdb |
Descriptor | TRYPSINOGEN, BOWMAN-BIRK PROTEINASE INHIBITOR PRECURSOR (3 entities in total) |
Functional Keywords | protease inhibitor, serine protease, bowman-birk inhibitor, hydrolase |
Biological source | Bos taurus (cattle) More |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 2 |
Total formula weight | 29755.83 |
Authors | Koepke, J.,Ermler, U.,Wenzl, G.,Flecker, P. (deposition date: 1999-10-15, release date: 2000-05-05, Last modification date: 2017-10-04) |
Primary citation | Koepke, J.,Ermler, U.,Warkentin, E.,Wenzl, G.,Flecker, P. Crystal structure of cancer chemopreventive Bowman-Birk inhibitor in ternary complex with bovine trypsin at 2.3 A resolution. Structural basis of Janus-faced serine protease inhibitor specificity. J.Mol.Biol., 298:477-491, 2000 Cited by PubMed: 10772864DOI: 10.1006/jmbi.2000.3677 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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