1D38

INFLUENCE OF AGLYCONE MODIFICATIONS ON THE BINDING OF ANTHRACYCLINE DRUGS TO DNA: THE MOLECULAR STRUCTURE OF IDARUBICIN AND 4-O-DEMETHYL-11-DEOXYDOXORUBICIN COMPLEXED TO D(CGATCG)

1D38 の概要

• エントリーDOI: 10.2210/pdb1d38/pdb
• 分子名称: DNA (5'-D(*CP*GP*AP*TP*CP*G)-3'), IDARUBICIN, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: right handed dna, double helix, complexed with drug, dna
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 2331.02

構造登録者

Gao, Y.-G.,Wang, A.H.-J. (登録日: 1991-04-23, 公開日: 1992-04-15, 最終更新日: 2024-02-07)

• 主引用文献: Gao, Y.G.,Wang, A.H.; Influence of aglycone modifications on the binding of anthracycline drugs to DNA: the molecular structure of idarubicin and 4-O-demethyl-11-deoxydoxorubicin complexed to d(CGATCG).; Anti-Cancer Drug Des., 6:137-149, 1991; PubMed: 1872945

実験手法

X-RAY DIFFRACTION (1.7 Å)