1D37
INFLUENCE OF AGLYCONE MODIFICATIONS ON THE BINDING OF ANTHRACYCLINE DRUGS TO DNA: THE MOLECULAR STRUCTURE OF IDARUBICIN AND 4-O-DEMETHYL-11-DEOXYDOXORUBICIN COMPLEXED TO D(CGATCG)
Summary for 1D37
Entry DOI | 10.2210/pdb1d37/pdb |
Descriptor | DNA (5'-D(*CP*GP*AP*TP*CP*G)-3'), 1-O-DEMETHYL-6-DEOXYDOXORUBICIN (3 entities in total) |
Functional Keywords | right handed dna, double helix, complexed with drug, dna |
Total number of polymer chains | 1 |
Total formula weight | 2322.71 |
Authors | Gao, Y.-G.,Wang, A.H.-J. (deposition date: 1991-04-23, release date: 1992-04-15, Last modification date: 2024-02-07) |
Primary citation | Gao, Y.G.,Wang, A.H. Influence of aglycone modifications on the binding of anthracycline drugs to DNA: the molecular structure of idarubicin and 4-O-demethyl-11-deoxydoxorubicin complexed to d(CGATCG). Anti-Cancer Drug Des., 6:137-149, 1991 Cited by PubMed: 1872945PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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