1CYD

CARBONYL REDUCTASE COMPLEXED WITH NADPH AND 2-PROPANOL

1CYD の概要

• エントリーDOI: 10.2210/pdb1cyd/pdb
• 分子名称: CARBONYL REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ISOPROPYL ALCOHOL, ... (4 entities in total)
• 機能のキーワード: short-chain dehydrogenase, oxidoreductase
• 由来する生物種: Mus musculus (house mouse)
• 細胞内の位置: Mitochondrion matrix: P08074
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 107178.78

構造登録者

Tanaka, N.,Nonaka, T.,Mitsui, Y. (登録日: 1995-09-01, 公開日: 1996-10-14, 最終更新日: 2024-02-07)

主引用文献

Tanaka, N.,Nonaka, T.,Nakanishi, M.,Deyashiki, Y.,Hara, A.,Mitsui, Y.
Crystal structure of the ternary complex of mouse lung carbonyl reductase at 1.8 A resolution: the structural origin of coenzyme specificity in the short-chain dehydrogenase/reductase family.
Structure, 4:33-45, 1996

PubMed Abstract: Mouse lung carbonyl reductase (MLCR) is a member of the short-chain dehydrogenase/reductase (SDR) family. Although it uses both NADPH and NADH as coenzymes, the structural basis of its strong preference for NADPH is unknown.

PubMed: 8805511
DOI: 10.1016/S0969-2126(96)00007-X

実験手法

X-RAY DIFFRACTION (1.8 Å)