1CVZ

CRYSTAL STRUCTURE ANALYSIS OF PAPAIN WITH CLIK148(CATHEPSIN L SPECIFIC INHIBITOR)

1CVZ の概要

• エントリーDOI: 10.2210/pdb1cvz/pdb
• 分子名称: PAPAIN, N1-(1-DIMETHYLCARBAMOYL-2-PHENYL-ETHYL)-2-OXO-N4-(2-PYRIDIN-2-YL-ETHYL)-SUCCINAMIDE (3 entities in total)
• 機能のキーワード: papain, clik148, cathepsin l inhibitor, sulfhydryl proteinase, hydrolase
• 由来する生物種: Carica papaya (papaya)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23859.81

構造登録者

Tsuge, H. (登録日: 1999-08-24, 公開日: 2000-08-30, 最終更新日: 2022-12-21)

• 主引用文献: Tsuge, H.,Nishimura, T.,Tada, Y.,Asao, T.,Turk, D.,Turk, V.,Katunuma, N.; Inhibition mechanism of cathepsin L-specific inhibitors based on the crystal structure of papain-CLIK148 complex.; Biochem.Biophys.Res.Commun., 266:411-416, 1999; PubMed: 10600517; DOI: 10.1006/bbrc.1999.1830

実験手法

X-RAY DIFFRACTION (1.7 Å)