1CTE

CRYSTAL STRUCTURES OF RECOMBINANT RAT CATHEPSIN B AND A CATHEPSIN B-INHIBITOR COMPLEX: IMPLICATIONS FOR STRUCTURE-BASED INHIBITOR DESIGN

1CTE の概要

• エントリーDOI: 10.2210/pdb1cte/pdb
• 分子名称: CATHEPSIN B, 2-PYRIDINETHIOL (3 entities in total)
• 機能のキーワード: thiol protease
• 由来する生物種: Rattus norvegicus (Norway rat)
• 細胞内の位置: Lysosome: P00787
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55694.03

構造登録者

Huber, C.P.,Jia, Z. (登録日: 1995-05-03, 公開日: 1995-07-31, 最終更新日: 2024-06-05)

• 主引用文献: Jia, Z.,Hasnain, S.,Hirama, T.,Lee, X.,Mort, J.S.,To, R.,Huber, C.P.; Crystal structures of recombinant rat cathepsin B and a cathepsin B-inhibitor complex. Implications for structure-based inhibitor design.; J.Biol.Chem., 270:5527-5533, 1995; PubMed: 7890671; DOI: 10.1074/jbc.270.10.5527

実験手法

X-RAY DIFFRACTION (2.1 Å)